International Network on Cancer, Infertility and Pregnancy

Mission Statement

The International Network on Cancer, Infertility and Pregnancy (INCIP) promotes research on cancer in pregnancy aiming to increase knowledge among health care workers and the public.

Recent research has shown that cancer treatment during pregnancy does not jeopardize maternal neither fetal chances. Focus is not solely on gynaecologic cancers though all cancers are included.

Collaboration with national or regional initiatives together with oncologists, obstetricians, perinatologists, paediatricians and other health workers is pivotal to improve the knowledge.

In addition, more experience is gained in young women who want to preserve their fertility.


The  primary objective is to establish an international registry on cancer during pregnancy and fertility preservation during cancer treatment. Data refer to the oncological, obstetrical and neonatal setting. For cancer in pregnancy, all cancer types (surgery, chemotherapy, radiotherapy) and treatments are included, including termination of pregnancy. Also for fertility preserving methods, all cancer types and treatment modalities are included. In addition, this platform should generate idea’s and facilitate the research for collaborations. The international registry contains data referring to both the cancer in pregnancy and fertility preservation populations.
Close collaboration with the ESGO Fertility Preservation task force is aimed for.


Watch the INCIP session on Fertility Preservation from ESGO 2015 congress on eAcademy.

Subscribe today to eAcademy and gain free access to view



Publications 2019:

  • Obstetric and maternal outcomes in patients diagnosed with Hodgkin lymphoma during pregnancy: a multicentre, retrospective, cohort study.
    Lancet Haematol. 2019 Sep 26. pii: S2352-3026(19)30195-4. doi: 10.1016/S2352-3026(19)30195-4. [Epub ahead of print]

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  • Gastric cancer during pregnancy: a report on 13 cases and review of the literature with focus on chemotherapy during pregnancy.
    Acta Obstet Gynecol Scand. 2019 Sep 16. doi: 10.1111/aogs.13731. [Epub ahead of print]

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  • Gynecologic cancers in pregnancy: guidelines based on a third international consensus meeting
    Ann Oncol. 2019 Aug 21. pii: mdz228. doi: 10.1093/annonc/mdz228. [Epub ahead of print]

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  • Endometrial cancer during pregnancy: management strategies
    Int J Gynecol Cancer. 2019 Sep;29(7):1221-1224. doi: 10.1136/ijgc-2019-000756. Epub 2019 Aug 20.

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  • Characteristics of patients with cervical cancer during pregnancy: a multicenter matched cohort study. An initiative from the International Network on Cancer, Infertility and Pregnancy
    Int J Gynecol Cancer. 2019 Mar 20. pii: ijgc-2018-000103. doi: 10.1136/ijgc-2018-000103. [Epub ahead of print]

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  • Management of cancer during pregnancy and current evidence of obstetric, neonatal and pediatric outcome: a review article
    Int J Gynecol Cancer. 2019 Jan 18. pii: ijgc-2018-000061. doi: 10.1136/ijgc-2018-000061. [Epub ahead of print]

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  • Effects of cancer treatment during pregnancy on fetal and child development
    Lancet Child Adolesc Health. 2017 Dec;1(4):302-310. doi: 10.1016/S2352-4642(17)30091-3. Epub 2017 Sep 29.

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  • Implementation of cancer treatment during pregnancy in daily practice: the important role of perinatologists
    Oncotarget. 2018 Aug 7;9(61):31795-31796. doi: 10.18632/oncotarget.25841. eCollection 2018 Aug 7.

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Publications 2018:

  • Kocián P et al. Management and outcome of colorectal cancer during pregnancy:
    report of 41 cases, Acta Chirurgica Belgica.

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  • Han, S.N., Amant, F., Cardonick, E.H. et al. Axillary staging for breast cancer during pregnancy: feasibility and safety of sentinel lymph node biopsy.
    Breast Cancer Res Treat (2018) 168: 551.

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  • de Haan J, Verheecke M, Van Calsteren K, Van Calster B, Shmakov RG, Mhallem Gziri M, Halaska MJ, Fruscio R, Lok CAR, Boere IA, Zola P, Ottevanger PB, de Groot CJM, Peccatori FA, Dahl Steffensen K, Cardonick EH, Polushkina E, Rob L, Ceppi L, Sukhikh GT, Han SN, Amant F; International Network on Cancer and Infertility Pregnancy (INCIP).
    Oncological management and obstetric and neonatal outcomes for women diagnosed with cancer during pregnancy: a 20-year international cohort study of 1170 patients.
    Lancet Oncol. 2018 Mar;19(3):337-346. doi: 10.1016/S1470-2045(18)30059-7. Epub 2018 Jan 26.

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  • Han et al. Eur Radiol (2018) 28: 1862.

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  • Verheecke M et al. Genetic and microscopic assessment of the human chemotherapy-exposed placenta reveals possible pathways contributive to fetal growth restriction.
    Placenta. 2018 Apr;64:61-70.This publication can be consulted through:

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Frédéric AMANT
University Hospitals of Leuven – Dept. Gynecological Oncology, Leuven – Belgium

If you have a special interest in the topic and would like to become a member of the network…

Only registered network members have the access to the international registery on cancer during pregnancy.

View the list of current INCIP members.

INCIP contact:

Frédéric AMANT
University Hospitals of Leuven – Dept. Gynecological Oncology, Leuven – Belgium

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