ESGO Exam Questions Examples (Single Best Answer Format)

Ovarian and Tubal cancer:

PARP inhibitor therapy is an option in platinum-sensitive high-grade serous ovarian cancer relapse. Which statement is accurate?

1. PARP inhibitors are most effective only in patients with a known germline BRCA.
2. PARP inhibitors are well-tolerated, with gastrointestinal symptoms being the most common side effect.
3. Maintenance therapy with PARP inhibitors is typically reserved for patients who achieve a complete response after chemotherapy.
4. The risk of secondary haematological malignancies exists but is relatively rare.

Pathology

Which of the following is a common feature of high-grade serous ovarian carcinoma on histopathology?

1. Extensive stromal invasion
2. Pseudostratified columnar epithelium
3. Psammoma bodies
4. Signet ring cells

Radiology

What is the purpose of sonohysterography according to the IETA consensus?

1. To measure the thickness of the myometrium
2. To act as a negative contrast agent by instilling fluid or gel into the uterine cavity
3. To avoid the use of ultrasound in endometrial assessment
4. To enhance the echogenicity of the ovaries

Systemic Therapy

A 60-year-old patient is referred because of recurrent endometrial cancer (endometrioid grade 3, pMMR). The initial treatment included hysterectomy, bilateral salpingo-oophorectomy, and sentinel lymph node biopsy, followed by adjuvant chemotherapy and external beam radiotherapy. After two years of follow-up, the patient has multiple lung and liver metastases on PET-CT and mild symptoms of recurrence. What is the optimal treatment?

1. The recommended second-line systemic treatment is combined therapy of pembrolizumb and lenvatinib.
2. The recommended second-line systemic treatment is non-platinum chemotherapy such as doxorubicin or paclitaxel.
3. The recommended second-line systemic treatment is endocrine therapy based on progestins.
4. Rechallenge with platinum-based chemotherapy is not an option for second-line treatment as it was already administrated as first-line treatment.

Vulvar cancer

According to the revised FIGO 2021 classification for vulvar cancer, which of the following is correct?

1. Infiltration of the upper third of the urethra is classified as prognostically equivalent to regional lymph node metastasis with extracapsular spread.
2. Infiltration of the upper third of the vagina is classified as prognostically equivalent to fixed or ulcerated inguinal lymph node metastasis.
3. Pelvic lymph node metastases are classified as prognostically equivalent to metastases in distant organs.
4. Ulcerated inguinal lymph node metastases are classified as prognostically equivalent to metastases in distant organs.